Factors associated with the recurrence of the treatments
The severity of oral mucositis may increase with each cycle of therapy due to partial healing of the oral mucosa.
Incomplete regeneration of the mucosa between each cycle.
Mucosa does not fully regenerate after cycle 1
The effects of chemotherapy on the mucosa can be more severe than previous cycle
This is a schematic representation of the development of mucositis during cycles of chemotherapy.
- Risk and severity of oral mucositis is increased if it occurs in the previous cycle of therapy8
- Patients who develop oral mucositis in cycle 1 are approximately four times more likely to develop oral mucositis in cycle 224