Patients & Caregivers

Oral Mucositis

Caphosol^®

Support Programs

Caphosol Home Delivery Program - NEW!

Healthcare Professionals

Patient Programs

Caphosol Home Delivery Program - NEW!

Product Information

CAPHOSOL^®, a topical oral agent, is a U.S. patented, prescription medical product that lubricates the mucosa and may help to maintain the integrity of the oral cavity through its mineralizing potential. The distinguishing feature of CAPHOSOL is its high concentrations of calcium and phosphate ions. Calcium ions play a crucial role in several aspects of the inflammatory process, the blood clotting cascade, and tissue repair. Phosphate ions may be a valuable supplemental source of phosphates for damaged mucosal surfaces.

More Prescribing Options to Address Your Patients' Treatment Needs

Caphosol is a supersaturated calcium phosphate rinse. Each box comes with individual ampules of:

Phosphate solution (Caphosol A)
Calcium solution (Caphosol B)

(1 dose = 2 ampules, each 15mL, mixed together)

Now 2 Convenient Dispensing Packs

1 Week's Supply

A 30-dose weekly dispensing pack for short courses of therapy.

1 box, each containing:

30 15mL ampules of Caphosol A
30 15mL ampules of Caphosol B

(total available doses = 30)
(30 x 30mL = 900mL)

1 Month's Supply

A 120-dose monthly dispensing pack for longer courses of therapy and chronic conditions.

4 boxes, each containing:

30 15mL ampules of Caphosol A
30 15mL ampules of Caphosol B

(total available doses = 120)
(120 x 30mL = 3600mL)

Prescribing for Optimal Results is Simple

	For short courses of high-dose chemotherapy and/or radiotherapy resulting in short duration of oral mucositis		Sig: Use Q.I.D. or PRN⁶ 7 day’s supply = 1, 30-dose dispensing pack, 900mL Refills x 3
	For long courses of high-dose chemotherapy and/or radiotherapy resulting in prolonged duration of oral mucositis		Sig: Use Q.I.D. or PRN⁶ 30 day’s supply = 1, 120-dose dispensing pack, 3600mL Refills x 3
	For treatment of dry mouth (xerostomia)		Sig: Use 2-10 times per day or as instructed by physician⁶ 30 day’s supply = 1, 120-dose dispensing pack, 3600mL Refill until resolved

Caphosol is indicated for dryness of the mouth or throat (hyposalivation, xerostomia), regardless of the cause and regardless of whether the conditions are temporary or permanent. Caphosol is also indicated as an adjunct to standard oral care in treating the mucositis that may be caused by radiation or high dose chemotherapy. Relief of dryness of the oral mucosa in these conditions is associated with an amelioration of pain.

Please see full prescribing information.

Pivotal Study

Caphosol, used in combination with standard oral care, is superior to fluoride rinse alone in reducing the frequency, intensity and duration of oral mucositis in patients undergoing hematopoietic stem cell transplantation.

A Prospective, Randomized Trial for the Prevention of Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation (PDF, 156 KB)
AS Papas, RE Clark, G Martuscelli, KT O'Loughlin, E Johansen and KB Miller.
Bone Marrow Transplantation. 2003;31:705–712.

Caphosol Safety Information:

If Caphosol is swallowed accidently, no adverse effects are expected
There are no known interactions with other medications
Reported side effects have been rare and generally mild

Keep out of reach of children. For full prescribing information, please click here.

C-0157-08